TdT+ T-lymphoblastic populations are increased in Castleman disease, in Castleman disease in association with follicular dendritic cell tumors, and in angioimmunoblastic T-cell lymphoma.

@article{Ohgami2012TdTTP,
  title={TdT+ T-lymphoblastic populations are increased in Castleman disease, in Castleman disease in association with follicular dendritic cell tumors, and in angioimmunoblastic T-cell lymphoma.},
  author={Robert S Ohgami and Shuchun Zhao and Jane K Ohgami and Matthew O Leavitt and James L Zehnder and Robert B. West and Daniel Alan Arber and Yasodha Natkunam and Roger A. Warnke},
  journal={The American journal of surgical pathology},
  year={2012},
  volume={36 11},
  pages={1619-28}
}
T-lymphoblastic lymphoma is an aggressive neoplasm requiring prompt clinical treatment. Conversely, indolent T-lymphoblastic proliferation mimics T-lymphoblastic lymphoma but consists of a proliferation of non-neoplastic TdT+ T cells, requiring no treatment. Recently, we identified several cases of indolent T-lymphoblastic proliferations in extrathymic lymphoid tissues: 1 in a patient suffering from Castleman disease (CD) associated with a follicular dendritic cell sarcoma/tumor, 1 in a patient… CONTINUE READING