Tcf3 expression marks both stem and progenitor cells in multiple epithelia.

Abstract

The Lef/Tcf-family transcription factor Tcf3 has important roles in development, stem cell function and malignancy. Previous gain- and loss-of-function studies have suggested that Tcf3 is a mediator of self-renewal and an undifferentiated state in stem and progenitor cells in skin, but little is known of its role in other postnatal tissues. Here, we explore… (More)
DOI: 10.1242/dev.106989

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