TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages.

@article{Fisk2008TbRGG2AE,
  title={TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages.},
  author={John C. Fisk and Michelle L. Ammerman and Vladimir Presnyak and Laurie K. Read},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 34},
  pages={23016-25}
}
In the mitochondria of kinetoplastid protozoa, including Trypanosoma brucei, RNA editing inserts and/or deletes uridines from pre-mRNAs to produce mature, translatable mRNAs. RNA editing is carried out by several related multiprotein complexes known as editosomes, which contain all of the enzymatic components required for catalysis of editing. In addition, noneditosome accessory factors necessary for editing of specific RNAs have also been described. Here, we report the in vitro and in vivo… CONTINUE READING

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RNA Editing Accessory Factor TbRGG2 23024 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

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