Taxonomy proposal for Old World monkey adenoviruses: characterisation of several non-human, non-ape primate adenovirus lineages

@article{Pant2015TaxonomyPF,
  title={Taxonomy proposal for Old World monkey adenoviruses: characterisation of several non-human, non-ape primate adenovirus lineages},
  author={Laura Pant{\'o} and Iva I Podgorski and M{\'a}t{\'e} J{\'a}noska and Orsolya M{\'a}rk{\'o} and Bal{\'a}zs Harrach},
  journal={Archives of Virology},
  year={2015},
  volume={160},
  pages={3165 - 3177}
}
A species classification regarding Old World monkey adenoviruses is proposed. We determined the nucleotide sequences of PCR-amplified fragments from the genes of the IVa2, DNA-dependent DNA polymerase, penton base, and hexon proteins from every simian adenovirus (SAdV) serotype that originated from Old World monkeys for which the full genome sequence had not yet been published. We confirmed that the majority of Old Word monkey SAdVs belong to two previously established species. Interestingly… 

Genome analysis of four Old World monkey adenoviruses supports the proposed species classification of primate adenoviruses and reveals signs of possible homologous recombination.

Phylogenetic calculations implied that recombination events might have happened between different AdV species, andylogeny inference, based on the viral DNA-dependent DNA polymerase and the penton base protein, supported the species classification proposed earlier.

Genome Analyses of Ten New Ape Adenoviruses with Similarity to Human Mastadenovirus C

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Phylogenetic analysis indicated that the tentative novel AdVs cluster into two separate groups, which form the most basal branches among the primate AdVs, and therefore support the theory on the co-evolution of primate adenoviruses with their hosts.

Isolation and characterization of adenoviruses infecting endangered golden snub-nosed monkeys (Rhinopithecus roxellana)

It is reported for the first time the isolation and full-length genomic characterization of an adenovirus from the subfamily Colobinae, and it is revealed that this virus represents a novel species in the genus Mastadenovirus.

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Complete genome analysis confirms that the pygmy marmoset adenovirus is a variant of the skunk adenovirus 1 - Short communication.

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Non-Human Primate-Derived Adenoviruses for Future Use as Oncolytic Agents?

  • S. BotsR. Hoeben
  • Medicine, Biology
    International journal of molecular sciences
  • 2020
The similarities and differences between human- and NHP-derived adenoviruses in view of their use as oncolytic agents, including their genome organization, receptor use, replication and cell lysis, modulation of the host’s immune responses, as well as their pathogenicity in humans are discussed.