Taxane-Induced Neuropathic Pain: Current Evidence and Treating Strategies

@article{Pota2018TaxaneInducedNP,
  title={Taxane-Induced Neuropathic Pain: Current Evidence and Treating Strategies},
  author={V. Pota and M. Passavanti and P. Sansone and M. Barbarisi and M. Pace and C. Aurilio},
  journal={Journal of Pain and Relief},
  year={2018},
  volume={7},
  pages={1-6}
}
  • V. Pota, M. Passavanti, +3 authors C. Aurilio
  • Published 2018
  • Medicine
  • Journal of Pain and Relief
  • Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling adverse event of most of commonly used antineoplastic agents. Previous studies have focused on several chemotherapeutic agents and reported that CIPN incidence varies from 19% to >85%. The mechanisms underlying CIPN are currently unknown. However, different theories have been proposed including microtubules dysfunction, mitochondrial dysfunction and mitochondrial toxicity, Glial pathway, substance P pathway, adenosine receptor… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 51 REFERENCES
    Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein).
    • 10,941
    Antidepressants for neuropathic pain.
    • 501
    Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis
    • 420
    • Open Access
    Chemotherapy-induced peripheral neurotoxicity
    • 188
    Analgesia Mediated by the TRPM8 Cold Receptor in Chronic Neuropathic Pain
    • 318
    • Open Access