Tauroursodeoxycholic Acid Reduces Arterial Stiffness and Improves Endothelial Dysfunction in Type 2 Diabetic Mice.

@article{Battson2017TauroursodeoxycholicAR,
  title={Tauroursodeoxycholic Acid Reduces Arterial Stiffness and Improves Endothelial Dysfunction in Type 2 Diabetic Mice.},
  author={Micah L. Battson and Dustin M Lee and Dillon K Jarrell and Shoufei Hou and Kayl E Ecton and Anna B Phan and Christopher L Gentile},
  journal={Journal of vascular research},
  year={2017},
  volume={54 5},
  pages={
          280-287
        }
}
BACKGROUND/AIMS Endoplasmic reticulum (ER) stress has emerged as a potential mechanism contributing to diabetes and its comorbidities. However, the importance of ER stress in diabetic vascular dysfunction is unclear. The purpose of this study was to examine the effects of the ER stress inhibitor, tauroursodeoxycholic acid (TUDCA), on arterial stiffness and… CONTINUE READING