Taurine protection of PC12 cells against endoplasmic reticulum stress induced by oxidative stress

@inproceedings{Pan2010TaurinePO,
  title={Taurine protection of PC12 cells against endoplasmic reticulum stress induced by oxidative stress },
  author={Chunliu Pan and Grace S Giraldo and Howard M Prentice and J. Y. Wu},
  booktitle={Journal of Biomedical Science},
  year={2010}
}
Taurine is a free amino acid present in high concentrations in a variety of organs of mammalians. As an antioxidant, taurine has been found to protect cells against oxidative stress, but the underlying mechanism is still unclear. In this report, we present evidence to support the conclusion that taurine exerts a protective function against endoplasmic reticulum (ER) stress induced by H2O2 in PC 12 cells. Oxidative stress was introduced by exposure of PC 12 cells to 250 uM H2O2 for 4 hours. It… CONTINUE READING
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