Tau-focused immunotherapy for Alzheimer's disease and related tauopathies.

Abstract

Immunotherapies targeting the amyloid-beta (Abeta) peptide in Alzheimer's disease (AD) have consistently been effective in mouse studies and shown promise in clinical trials, although some setbacks have occurred. First, encephalitis was observed in a small subset of patients. More recent autopsy data from a few subjects suggests that clearance of Abeta… (More)

Topics

Cite this paper

@article{Sigurdsson2009TaufocusedIF, title={Tau-focused immunotherapy for Alzheimer's disease and related tauopathies.}, author={Einar M. Sigurdsson}, journal={Current Alzheimer research}, year={2009}, volume={6 5}, pages={446-50} }