Tau Strains and Their Propagation in Experimental Disease Models

Abstract

Tauopathies encompass a broad family of neurodegenerative diseases, including Alzheimer’s disease, which are characterized by the fibrillization of the microtubuleassociated tau protein. The normal function of tau is to stabilize and promote the assembly of microtubules in neuronal axons. Sequestration of tau into amyloid fibrils results in destabilization… (More)

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Cite this paper

@inproceedings{Giachin2015TauSA, title={Tau Strains and Their Propagation in Experimental Disease Models}, author={Gabriele Giachin and Kyle P. McHugh and Olga A. Morozova and David W. Colby}, year={2015} }