Taste perception and coding in the periphery

  title={Taste perception and coding in the periphery},
  author={Makoto Sugita},
  journal={Cellular and Molecular Life Sciences CMLS},
Recent identification of taste receptors and their downstream signaling molecules, expressed in taste receptor cells, led to the understanding of taste coding in the periphery. Ion channels appear to mediate detection of salty and sour taste. The sensations of sweet, umami and bitter taste are initiated by the interaction of sapid molecules with the G-protein-coupled receptors T1Rs and T2Rs. Mice lacking either PLCβ2 or TRPM5 diminish behavioral and nerve responses to sweet, umami and bitter… CONTINUE READING

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