Taspoglutide: a long acting human glucagon-like polypeptide-1 analogue.

  title={Taspoglutide: a long acting human glucagon-like polypeptide-1 analogue.},
  author={Kjetil Retterst\ol},
  journal={Expert opinion on investigational drugs},
  volume={18 9},
BACKGROUND Taspoglutide (R1583/BIM51077) is a new anti diabetic drug from Hoffmann-La Roche. The compound is to be administered as a subcutaneous injection once weekly and is also effective given bi-weekly. It is a long acting 10% formulation of (Aib 8-35) human glucagon-like polypeptide-1 (7 - 36 amides) with 93% homology with the native polypeptide. It activates the glucagon-like polypeptide-1 receptor. Phase III trials are currently in process. OBJECTIVE To provide a critical review of… CONTINUE READING
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