Tasmanian devil facial tumor disease: Insights into reduced tumor surveillance from an unusual malignancy

@article{ONeill2010TasmanianDF,
  title={Tasmanian devil facial tumor disease: Insights into reduced tumor surveillance from an unusual malignancy},
  author={I. O'Neill},
  journal={International Journal of Cancer},
  year={2010},
  volume={127}
}
  • I. O'Neill
  • Published 2010
  • Biology, Medicine
  • International Journal of Cancer
Tasmanian devil facial tumor disease (DFTD) is a highly aggressive cancer involving the facial tissues that currently presents a serious extinction risk for the Tasmanian devil population. Although the histogenesis is uncertain, an origin from a neural crest cell‐lineage is considered likely. Epidemiological, cytogenetic and immunological data all support the premise that DFTD arose from a single tumor clone from an individual diseased animal, and is being transmitted between individual animals… Expand
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