Task-specific hypoactivation in prefrontal and temporoparietal brain regions during motor inhibition and task switching in medication-naive children and adolescents with attention deficit hyperactivity disorder.

@article{Smith2006TaskspecificHI,
  title={Task-specific hypoactivation in prefrontal and temporoparietal brain regions during motor inhibition and task switching in medication-naive children and adolescents with attention deficit hyperactivity disorder.},
  author={Anna B. Smith and Eric Taylor and Michael J. Brammer and Brian Toone and Katya Rubia},
  journal={The American journal of psychiatry},
  year={2006},
  volume={163 6},
  pages={
          1044-51
        }
}
OBJECTIVE A relatively small number of functional imaging studies of attention deficit hyperactivity disorder (ADHD) have shown abnormal prefrontal and striatal brain activation during tasks of motor response inhibition. However, the potential confound of previous medication exposure has not yet been addressed, and no functional imaging study exists to date on medication-naive children and adolescents with ADHD. The aim of this study was to investigate the neural substrates of a range of motor… 
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