Targets to treat androgen excess in polycystic ovary syndrome

@article{LuqueRamrez2015TargetsTT,
  title={Targets to treat androgen excess in polycystic ovary syndrome},
  author={Manuel Luque‐Ram{\'i}rez and H{\'e}ctor Francisco Escobar-Morreale},
  journal={Expert Opinion on Therapeutic Targets},
  year={2015},
  volume={19},
  pages={1545 - 1560}
}
Introduction: The polycystic ovary syndrome (PCOS) is a common androgen disorder in reproductive-aged women. Excessive biosynthesis and secretion of androgens by steroidogenic tissues is its central pathogenetic mechanism. Areas covered: The authors review the potential targets and new drugs to treat androgen excess in PCOS. Besides our lab’s experience, a systematic search (MEDLINE, Cochrane library, ClinicalTriasl.gov, EU Clinical Trials Register and hand-searching) regarding observational… 

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Steroid Hormone Profiling in Hyperandrogenism and Non-hyperandrogenism Women with Polycystic Ovary Syndrome

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected women have marked

Antiandrogenic Contraceptives Increase Serum Adiponectin in Obese Polycystic Ovary Syndrome Patients

TLDR
The present results might suggest a direct inhibitory effect of androgen excess on adiponectin secretion by adipocytes in obese PCOS women, supporting the hypothesis that androgens excess contributes to adipocyte dysfunction in these women.
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