Targets for cancer therapy in childhood sarcomas.

@article{Wachtel2010TargetsFC,
  title={Targets for cancer therapy in childhood sarcomas.},
  author={Marco Wachtel and Beat W. Sch{\"a}fer},
  journal={Cancer treatment reviews},
  year={2010},
  volume={36 4},
  pages={318-27}
}
Development of chemotherapeutic treatment modalities resulted in a dramatic increase in the survival of children with many types of cancer. Still, in case of some pediatric cancer entities including rhabdomyosarcoma, osteosarcoma and Ewing's sarcoma, survival of patients remains dismal and novel treatment approaches are urgently needed. Therefore, based on the concept of targeted therapy, numerous potential targets for the treatment of these cancers have been evaluated pre-clinically or in some… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 197 references

Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2002
View 9 Excerpts
Highly Influenced

A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2008
View 4 Excerpts
Highly Influenced

VEGF blockade decelerates the growth of a murine experimental osteosarcoma.

International journal of oncology • 2008
View 17 Excerpts
Highly Influenced

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