Targets and consequences of protein SUMOylation in neurons

@article{Wilkinson2010TargetsAC,
  title={Targets and consequences of protein SUMOylation in neurons},
  author={K. A. Wilkinson and Y. Nakamura and J. Henley},
  journal={Brain Research Reviews},
  year={2010},
  volume={64},
  pages={195-212}
}
  • K. A. Wilkinson, Y. Nakamura, J. Henley
  • Published 2010
  • Biology, Medicine
  • Brain Research Reviews
  • The post-translational modification of proteins is critical for the spatial and temporal regulation of signalling cascades. This is especially important in the CNS where the processes affecting differentiation, growth, targeting and communication between neurones are highly complex and very tightly regulated. In recent years it has emerged that modification of proteins by members of the SUMO (small ubiquitin-related modifier) family of proteins play key roles in neuronal function. SUMOylation… CONTINUE READING
    139 Citations
    Regulation of Neuronal Protein Trafficking and Translocation by SUMOylation
    • 5
    • PDF
    Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.
    • 118
    • PDF
    SUMO1 Affects Synaptic Function, Spine Density and Memory
    • 34
    • PDF
    Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity
    • 19
    • PDF

    References

    SHOWING 1-10 OF 178 REFERENCES
    Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction
    • 185
    • PDF
    Protein SUMOylation in neuropathological conditions.
    • 38
    Analysis of SUMO-1 modification of neuronal proteins containing consensus SUMOylation motifs
    • 49
    SUMO on the road to neurodegeneration.
    • 169
    Regulation and Function of SUMO Modification*
    • 123
    • PDF
    Modification in reverse: the SUMO proteases.
    • 487
    Developmental regulation of Ubc9 in the rat nervous system.
    • 25
    • PDF
    SUMOylation regulates kainate receptor-mediated synaptic transmission
    • 70
    Protein modification by SUMO.
    • E. Johnson
    • Biology, Medicine
    • Annual review of biochemistry
    • 2004
    • 1,540
    • PDF