Targeting tumor neovasculature in non-small-cell lung cancer.

  title={Targeting tumor neovasculature in non-small-cell lung cancer.},
  author={Athanasios G. Pallis and Konstantinos Syrigos},
  journal={Critical reviews in oncology/hematology},
  volume={86 2},
Recent insight into the molecular biology of cancer and mechanisms of tumorigenesis, has allowed for the identification of several potential molecular targets and the development of novel "targeted therapies". One of the most active research fields in NSCLC is the discovery of therapies that target angiogenesis. The vascular endothelial growth factor (VEGF) pathway represents a crucial component of the tumor angiogenesis process. Two different strategies have been developed in clinical practice… CONTINUE READING
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