Targeting treatments for alcohol dependence: the pharmacogenetics of naltrexone.

@article{Oslin2006TargetingTF,
  title={Targeting treatments for alcohol dependence: the pharmacogenetics of naltrexone.},
  author={David W. Oslin and Wade H. Berrettini and Charles P O'brien},
  journal={Addiction biology},
  year={2006},
  volume={11 3-4},
  pages={397-403}
}
Alcohol dependence is one of the leading causes of morbidity worldwide, yet only a minority of those afflicted engages in treatment. While increasing access to treatment is an important public health approach, increasing the success of treatment is also likely to lead to greater engagement. However, alcohol dependence is a complex disorder likely to consist of several biological subtypes. Recent evidence from a number of different studies has suggested that genetic variation in the mu-opioid… CONTINUE READING