Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms.


Intracellular parasites of the phylum Apicomplexa contain specialized rhoptry secretory organelles that have a crucial function in host-cell invasion and establishment of the parasitophorous vacuole. Here we show that localization of the Toxoplasma gondii rhoptry protein ROP2 is dependent on a YEQL sequence in the cytoplasmic tail that binds to µ-chain… (More)
DOI: 10.1038/35017090


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