Targeting to macrophages: role of physicochemical properties of particulate carriers--liposomes and microspheres--on the phagocytosis by macrophages.

@article{Ahsan2002TargetingTM,
  title={Targeting to macrophages: role of physicochemical properties of particulate carriers--liposomes and microspheres--on the phagocytosis by macrophages.},
  author={Fakhrul Ahsan and Isabel P Rivas and Mansoor A. Khan and Ana I Torres Suarez},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2002},
  volume={79 1-3},
  pages={29-40}
}
Heterogeneous functions of macrophages in human immune systems have renewed interest in targeting of drugs to these cells. Various carrier systems have emerged to deliver drugs to macrophages, albeit the efficacy, reliability and selectivity of these carriers are still in question. To date, the most extensively studied carriers are liposomes and microspheres. Various physicochemical properties of these carriers can alter their efficacy and specificity to a great extent. These properties include… CONTINUE READING

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