Targeting the synovial angiogenesis as a novel treatment approach to osteoarthritis.


Synovitis is a key feature in osteoarthritis and is associated with symptom severity. Synovial membrane inflammation is secondary to cartilage degradation which occurs in the early stage and is located adjacent to cartilage damage. This inflammation is characterized by the invasion and activation of macrophages and lymphocytes, the release in the joint… (More)
DOI: 10.1177/1759720X13514669


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