Targeting the immunoregulatory indoleamine 2,3 dioxygenase pathway in immunotherapy.

Abstract

Natural immune tolerance is a formidable barrier to successful immunotherapy to treat established cancers and chronic infections. Conversely, creating robust immune tolerance via immunotherapy is the major goal in treating autoimmune and allergic diseases, and enhancing survival of transplanted organs and tissues. In this review, we focus on a natural… (More)
DOI: 10.2217/IMT.09.21

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3 Figures and Tables