Targeting the Vessel Underdogs: Therapeutic Approaches for Microvessel Dysfunction in the Heart.

@article{LeBlanc2015TargetingTV,
  title={Targeting the Vessel Underdogs: Therapeutic Approaches for Microvessel Dysfunction in the Heart.},
  author={Amanda J LeBlanc and Christopher D. Nevitt},
  journal={Critical reviews in biomedical engineering},
  year={2015},
  volume={43 5-6},
  pages={
          473-89
        }
}
From an obscure and overlooked beginning, the function of the microvessels in the heart has received increasing attention after the Women's Ischemia Syndrome Evaluation study concluded roughly a decade ago. This review defines the contribution of the coronary microcirculation in the development of heart disease and focuses on the therapeutic methods to reverse coronary microvascular dysfunction. Tissue engineering approaches in the past have largely neglected vascular cells in the attempts to… CONTINUE READING