Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease.

@article{JuradoCoronel2016TargetingTN,
  title={Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease.},
  author={Juan Camilo Jurado-Coronel and Marco Fidel Avila-Rodriguez and Francisco Capani and Janneth Gonz{\'a}lez and Valentina Echeverria Moran and George E Barreto},
  journal={Current pharmaceutical design},
  year={2016},
  volume={22 10},
  pages={
          1305-11
        }
}
Parkinson's disease (PD) is a relatively common disorder of the Central Nervous System (CNS), whose etiology is characterized by a selective and progressive degeneration of dopaminergic neurons, and the presence of Lewy bodies in the pars compacta of the substantia nigra, and gaping dopamine depletion in the striatum. Patients with this disease suffer from tremors, slowness of movements, gait instability, and rigidity. These patients may also present functional disability, reduced quality of… CONTINUE READING
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