Targeting the MET gene for the treatment of non-small-cell lung cancer.

Abstract

Recently, a better understanding of the specific mechanisms of oncogene addiction has led to the development of antitumor strategies aimed at blocking these abnormalities in different malignancies, including lung cancer. These abnormalities trigger constitutive activation of tyrosine kinase receptors (RTKs) involved in fundamental cell mechanisms such as… (More)
DOI: 10.1016/j.critrevonc.2013.11.006

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