Targeting the Androgen Receptor in Breast Cancer

@article{Chia2015TargetingTA,
  title={Targeting the Androgen Receptor in Breast Cancer},
  author={Kee Ming Chia and Megan O'Brien and Myles A Brown and Elgene Lim},
  journal={Current Oncology Reports},
  year={2015},
  volume={17},
  pages={1-6}
}
The androgen receptor (AR) is expressed in the majority of breast cancer and across the three main breast cancer subtypes. Historically, the oncogenic role of AR has best been described in molecular apocrine breast cancers, an estrogen receptor (ER)−/AR+ subtype which has a steroid response signature similar to that in the ER-positive breast cancer. The signalling effect of AR is likely to be different across breast cancer subtypes, and particularly important is its interaction with ER… 

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