Targeting survivin in cancer: patent review.

@article{Kanwar2010TargetingSI,
  title={Targeting survivin in cancer: patent review.},
  author={J. R. Kanwar and Sishir Kumar Kamalapuram and Rupinder Kaur Kanwar},
  journal={Expert opinion on therapeutic patents},
  year={2010},
  volume={20 12},
  pages={
          1723-37
        }
}
IMPORTANCE OF THE FIELD Survivin is a prominent anti-apoptotic molecule expressed widely in the majority of cancers. Overexpression of survivin leads to uncontrolled cancer cell growth and drug resistance. Efficient downregulation of survivin expression and its functions can sensitise the tumour cells to various therapeutic interventions such as chemotherapeutic agents leading to cell apoptosis. AREAS COVERED IN THIS REVIEW The article thoroughly analyses up-to-date information on the… CONTINUE READING
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