Targeting somatostatin receptors using in situ-bioconjugated fluorescent nanoparticles.

@article{Sreenivasan2012TargetingSR,
  title={Targeting somatostatin receptors using in situ-bioconjugated fluorescent nanoparticles.},
  author={Varun K A Sreenivasan and Eun Jun Kim and Ann K Goodchild and Mark Connor and Andrei V. Zvyagin},
  journal={Nanomedicine},
  year={2012},
  volume={7 10},
  pages={
          1551-60
        }
}
AIM The author's group report, for the first time, on the development of a quantum dot (QD)-based fluorescent somatostatin (somatotropin release-inhibiting factor [SRIF]) probe that enables specific targeting of somatostatin receptors. Receptor-mediated endocytosis of SRIF was imaged using this probe. MATERIALS & METHODS Biotinylated SRIF-analog (SRIF-B) and streptavidin (Sav)-coated QDs were used for the probe synthesis. A dye-labeled streptavidin complex was used to evaluate the effect of… 
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