Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions

@inproceedings{Iwaszkiewicz2013TargetingPO,
  title={Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions},
  author={Katerina S. Iwaszkiewicz and Jennifer J. Schneider and S. Jack Hua},
  booktitle={Front. Pharmacol.},
  year={2013}
}
Mechanisms of endogenous pain control are significant. Increasing studies have clearly produced evidence for the clinical usefulness of opioids in peripheral analgesia. The immune system uses mechanisms of cell migration not only to fight pathogens but also to control pain and inflammation within injured tissue. It has been demonstrated that peripheral inflammatory pain can be effectively controlled by an interaction of immune cell-derived opioid peptides with opioid receptors on peripheral… CONTINUE READING
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