Targeting pericyte differentiation as a strategy to modulate kidney fibrosis in diabetic nephropathy.

Abstract

Pericytes are a heterogeneous group of extensively branched cells located in microvessels where they make focal contacts with endothelium. Pericytes stabilize blood vessels, regulate vascular tone, synthesize matrix, participate in repair, and serve as progenitor cells, among other functions. Recent work has highlighted the role of pericytes and pericyte… (More)
DOI: 10.1016/j.semnephrol.2012.07.009

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