Targeting oxidative stress component in the therapeutics of epilepsy.

  title={Targeting oxidative stress component in the therapeutics of epilepsy.},
  author={Faizul Azam and M. V. R. Prasad and Neelaveni Thangavel},
  journal={Current topics in medicinal chemistry},
  volume={12 9},
The role of free radical-mediated reactions in human neuropathology continues to attract significant interest. Oxidative injury produced by free radicals may play a role in the initiation and progression of epilepsy and, therapies aimed at reducing oxidative stress may ameliorate tissue damage and favorably alter the clinical course. The prevalence of epilepsy increases with age, and mitochondrial oxidative stress is a leading mechanism of aging and age-related degenerative disease, signifying… CONTINUE READING


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