Targeting of herpesvirus capsid transport in axons is coupled to association with specific sets of tegument proteins.

@article{Luxton2005TargetingOH,
  title={Targeting of herpesvirus capsid transport in axons is coupled to association with specific sets of tegument proteins.},
  author={George W G Luxton and Sarah Haverlock and Kelly Elizabeth Coller and Sarah Elizabeth Antinone and Andrew Pincetic and Gregory A Smith},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2005},
  volume={102 16},
  pages={5832-7}
}
The capsids of neurotropic herpesviruses have the remarkable ability to move in specific directions within axons. By modulating bidirectional capsid transport to favor either retrograde (minus-end) or anterograde (plus-end) motion, these viruses travel to sensory ganglia or peripheral tissue at specific stages of infection. By using correlative motion analysis to simultaneously monitor the trafficking of distinct viral proteins in living neurons, we demonstrate that viral "tegument" proteins… CONTINUE READING

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