Targeting of cardiac muscle titin fragments to the Z-bands and dense bodies of living muscle and non-muscle cells.

@article{Ayoob2000TargetingOC,
  title={Targeting of cardiac muscle titin fragments to the Z-bands and dense bodies of living muscle and non-muscle cells.},
  author={Joseph C. Ayoob and Kenan K. Turnacioglu and Balraj Mittal and Jean M. Sanger and Joseph W. Sanger},
  journal={Cell motility and the cytoskeleton},
  year={2000},
  volume={45 1},
  pages={67-82}
}
A 6.5-kb N-terminal region of embryonic chick cardiac titin, including the region previously reported as part of the protein zeugmatin, has been sequenced, further demonstrating that zeugmatin is part of the N-terminal region of titin, and not a separate Z-band protein. This Z-band region of cardiac titin, from both 7- and 19-day embryos as well as from adult animals, was found to contain six different small motifs, termed z-repeats [Gautel et al., 1996: J. Cell Sci. 109:2747-2754], of… CONTINUE READING

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