Targeting of Rab GTPases to cellular membranes.

  title={Targeting of Rab GTPases to cellular membranes.},
  author={Bassam R Ali and Miguel C. Seabra},
  journal={Biochemical Society transactions},
  volume={33 Pt 4},
Rab proteins are members of the superfamily of Ras-like small GTPases and are involved in several cellular processes relating to membrane trafficking and organelle mobility throughout the cell. Like other small GTPases, Rab proteins are initially synthesized as soluble proteins and for membrane attachment they require the addition of lipid moiety(ies) to specific residues of their polypeptide chain. Despite their well-documented roles in regulating cellular trafficking, Rab proteins own… CONTINUE READING


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Cell (Cambridge, Mass

  • M. Zerial
  • 2004

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