Targeting of Proteins of the Striatin Family to Dendritic Spines: Role of the Coiled‐Coil Domain

@article{Gaillard2006TargetingOP,
  title={Targeting of Proteins of the Striatin Family to Dendritic Spines: Role of the Coiled‐Coil Domain},
  author={Stéphane Gaillard and Yannick Bailly and Marion Benoist and Tatiana V. Rakitina and Jean-Pierre Kessler and Laure Fronzaroli‐Molinieres and B{\'e}n{\'e}dicte Dargent and Francis Castets},
  journal={Traffic},
  year={2006},
  volume={7}
}
Striatin, SG2NA and zinedin, the three mammalian members of the striatin family are multimodular WD‐repeat, calmodulin and calveolin‐binding proteins. These scaffolding proteins, involved in both signaling and trafficking, are highly expressed in neurons. Using ultrastructural immunolabeling, we showed that, in Purkinje cells and hippocampal neurons, SG2NA is confined to the somatodendritic compartment with the highest density in dendritic spines. In cultured hippocampal neurons, SG2NA is also… 

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