Targeting normal and neoplastic tissues in the rat jejunum and colon with boronated, cationic acrylamide copolymers.

@article{Azab2005TargetingNA,
  title={Targeting normal and neoplastic tissues in the rat jejunum and colon with boronated, cationic acrylamide copolymers.},
  author={Abdel-Kareem Azab and Morris Srebnik and Victoria Doviner and Abraham Rubinstein},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2005},
  volume={106 1-2},
  pages={14-25}
}
A series of boronated cationic copolymers, composed of different ratios of acrylamide, N-acryloyl-3-aminophenylboronic acid and N-acryloyl-diaminoethane (the cationic moiety), were prepared with the intention of localizing boron neutron capture therapy (BNCT) in experimentally induced polyps on the luminal side of the gut of the rat. The goals of this study were to: (a) test the effect of cationization of the boronated copolymers on their uptake by polyps and normal adjacent epithelium; (b… CONTINUE READING
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…