Targeting neurosteroidogenesis as therapy for PTSD

  title={Targeting neurosteroidogenesis as therapy for PTSD},
  author={Graziano Pinna},
  booktitle={Front. Pharmacol.},
Posttraumatic stress disorder (PTSD) is a severe condition resulting from exposure to traumatic events, such as combat situations, sexual assault, serious injury or the threat of death. Symptoms include disturbing recurring flashbacks, avoidance or numbing of memories of the event, and hyperarousal, which continue for more than a month after the traumatic event. Reduced cortical GABA (Kugaya et al., 2003) and cebrospinal fluid (CSF) allopregnanolone levels (Rasmusson et al., 2006) that… CONTINUE READING
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