Targeting muscle stem cell intrinsic defects to treat Duchenne muscular dystrophy

@inproceedings{Dumont2016TargetingMS,
  title={Targeting muscle stem cell intrinsic defects to treat Duchenne muscular dystrophy},
  author={Nicolas Dumont and Michael Rudnicki},
  booktitle={npj Regenerative Medicine},
  year={2016}
}
Duchenne muscular dystrophy (DMD) is a genetic disease characterised by skeletal muscle degeneration and progressive muscle wasting, which is caused by loss-of-function mutations in the DMD gene that encodes for the protein dystrophin. Dystrophin has critical roles in myofiber stability and integrity by connecting the actin cytoskeleton to the extracellular… CONTINUE READING