Targeting mitochondrial alterations to prevent type 2 diabetes--evidence from studies of dietary redox-active compounds.

@article{Cheng2014TargetingMA,
  title={Targeting mitochondrial alterations to prevent type 2 diabetes--evidence from studies of dietary redox-active compounds.},
  author={Zhiyong Cheng and Eva M. Schmelz and Dongmin Liu and Matthew W. Hulver},
  journal={Molecular nutrition & food research},
  year={2014},
  volume={58 8},
  pages={1739-49}
}
As a growing epidemic, type 2 diabetes mellitus (T2DM) has significantly affected the individual's quality of life and economy of the society. Understanding the mechanisms of the disease and discovery of new therapeutic options has become more urgent than ever before. Mitochondrial alterations (e.g. functional alterations, and impaired biogenesis and dynamics) are strongly associated with the development of T2DM. Accumulation of reactive oxygen species or intermediates of incomplete fatty acid… CONTINUE READING
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