Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance.


Although chemotherapy is an important therapeutic strategy for cancer treatment, it fails to eliminate all tumor cells due to intrinsic or acquired drug resistance, which is the most common cause of tumor recurrence. Emerging evidence suggests an intricate role of cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT)-type cells in anticancer… (More)
DOI: 10.1016/j.drup.2010.07.001


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