Targeting membrane androgen receptors in tumors

  title={Targeting membrane androgen receptors in tumors},
  author={F. Lang and Konstantinos Alevizopoulos and C. Stournaras},
  journal={Expert Opinion on Therapeutic Targets},
  pages={951 - 963}
  • F. Lang, Konstantinos Alevizopoulos, C. Stournaras
  • Published 2013
  • Biology, Medicine
  • Expert Opinion on Therapeutic Targets
  • Introduction: In the last decade androgen actions that are originated from non-genomic, rapid signaling have been described in a large number of cell models and tissues. These effects are initiated through the stimulation of membrane androgen-binding sites or receptors (mAR). Although the molecular identity of mARs remains elusive, their activation is known to trigger multiple non-genomic signaling cascades and to regulate numerous cell responses. In recent years specific interest is being paid… CONTINUE READING
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