Targeting malignant mitochondria with therapeutic peptides.


The current status of peptides that target the mitochondria in the context of cancer is the focus of this review. Chemotherapy and radiotherapy used to kill tumor cells are principally mediated by the process of apoptosis that is governed by the mitochondria. The failure of anticancer therapy often resides at the level of the mitochondria. Therefore, the… (More)


Cite this paper

@article{Constance2012TargetingMM, title={Targeting malignant mitochondria with therapeutic peptides.}, author={Jonathan E. Constance and Carol S Lim}, journal={Therapeutic delivery}, year={2012}, volume={3 8}, pages={961-79} }