Targeting malaria parasite proteins to the erythrocyte.

  title={Targeting malaria parasite proteins to the erythrocyte.},
  author={Thomas J. Templeton and Kirk W. Deitsch},
  journal={Trends in parasitology},
  volume={21 9},
The intraerythrocytic stages of the protozoan parasite Plasmodium falciparum reside within a parasitophorous vacuole (PV) and set up unique "extraparasite, intraerythrocyte" protein-trafficking pathways that target parasite-encoded proteins to the erythrocyte cytoplasm and cell surface. Two recent articles report the identification of trafficking motifs that regulate the transport of parasite-encoded proteins across the PV. These articles greatly aid the annotation of the parasite "secretome… CONTINUE READING