Targeting lymphangiogenesis to prevent tumour metastasis

Abstract

Recent studies involving animal models of cancer and clinicopathological analyses of human tumours suggest that the growth of lymphatic vessels (lymphangiogenesis) in or nearby tumours is associated with the metastatic spread of cancer. The best validated molecular signalling system for tumour lymphangiogenesis involves the secreted proteins vascular… (More)
DOI: 10.1038/sj.bjc.6603120

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