Targeting low molecular weight cyclin E (LMW-E) in breast cancer


Low molecular weight cyclin E (LMW-E) plays an important oncogenic role in breast cancer. LMW-E, which is not found in normal tissue, can promote the formation of aggressive tumors and can lead to increased genomic instability and tumorigenesis. Additionally, breast cancer patients whose tumors express LMW-E have a very poor prognosis. Therefore, we… (More)
DOI: 10.1007/s10549-011-1638-4


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