Targeting ion channels for the treatment of gastrointestinal motility disorders.

@article{Beyder2012TargetingIC,
  title={Targeting ion channels for the treatment of gastrointestinal motility disorders.},
  author={Arthur Beyder and Gianrico Farrugia},
  journal={Therapeutic advances in gastroenterology},
  year={2012},
  volume={5 1},
  pages={5-21}
}
Gastrointestinal (GI) functional and motility disorders are highly prevalent and responsible for long-term morbidity and sometimes mortality in the affected patients. It is estimated that one in three persons has a GI functional or motility disorder. However, diagnosis and treatment of these widespread conditions remains challenging. This partly stems from the multisystem pathophysiology, including processing abnormalities in the central and peripheral (enteric) nervous systems and motor… CONTINUE READING

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