Targeting inflammation using selective glucocorticoid receptor modulators.

@article{Bosscher2010TargetingIU,
  title={Targeting inflammation using selective glucocorticoid receptor modulators.},
  author={Karolien De Bosscher and Guy Haegeman and Dirk Elewaut},
  journal={Current opinion in pharmacology},
  year={2010},
  volume={10 4},
  pages={497-504}
}
Glucocorticoids have been used since several decades in a variety of diseases in view of their potent anti-inflammatory properties. Nevertheless, the widespread use of glucocorticoids is hampered by the risk of side effects. Because the effects of glucocorticoids are mediated at large through interaction with the glucocorticoid receptor, which results in anti-inflammatory effects as well as side effects, much attention has been given to understanding the molecular regulation. Over the past… CONTINUE READING