Targeting hirsutism: a new approach

  title={Targeting hirsutism: a new approach},
  author={Boaz Kurtis and Sarah Brenner},
  journal={Sexuality, Reproduction and Menopause},
Hirsutism, the appearance of facial hair on women in a male pattern distribution, is a problem with potential medical, social, and psychological implications for millions of women. Hirsutism can reflect the presence of an underlying systemic disease, namely one that results in hyperandrogenic states, or it may seem to be idiopathic. Many methods of treatment have been used over the years, from pharmacological and surgical treatment for underlying disease to mechanical means of hair removal. We… Expand


Management of Hirsutism
This review reports its own experience with, and literature studies of, the pharmacological management of hirsutism in women with hyperandrogenism or with normal serum androgen levels and regular ovulatory menstrual cycles. Expand
Prevalence of idiopathic hirsutism.
  • E. Carmina
  • Medicine
  • European journal of endocrinology
  • 1998
Evaluated hirsute women evaluated as outpatients at the Department of Endocrinology of the University of Palermo, Italy found 36 women had regular ovulatory cycles and normal androgen levels and were diagnosed as being affected by idiopathic hirsutism. Expand
Increased 5α-reductase activity in idiopathic hirsutism*†
In vitro 5 α -RA in IH appears to be independent of serum androgen levels and is, therefore, an inherent abnormality, because hirsutism in these patients may be explained on the basis of increased skin 5α -RA. Expand
Human dermal safety studies with eflornithine HCl 13.9% cream (Vaniqa), a novel treatment for excessive facial hair.
The results demonstrate that eflornithine HCl 13.9% cream does not have contact sensitising, photocontact allergic or phototoxic properties, and has a favourable dermal safety profile appropriate for a topical treatment to be applied routinely. Expand
Color Atlas and Synopsis of Clinical Dermatology
The color atlas and synopsis of clinical dermatology is presented as well as a review of existing works on the subject and some new ideas are proposed. Expand
The eflornithine story.
  • P. Coyne
  • Medicine
  • Journal of the American Academy of Dermatology
  • 2001