Targeting epidermal growth factor receptor: novel therapeutics in the management of cancer.

@article{Khalil2003TargetingEG,
  title={Targeting epidermal growth factor receptor: novel therapeutics in the management of cancer.},
  author={Mazen Y. Khalil and Jennifer R Grandis and Dong M Shin},
  journal={Expert review of anticancer therapy},
  year={2003},
  volume={3 3},
  pages={367-80}
}
Overexpression of epidermal growth factor receptor (EGFR) in epithelial tumors, including head and neck, lung, breast, colon and other solid tumors, has frequently been correlated with poor prognosis, thus stimulating efforts to develop new cancer therapies that target EGFR. Monoclonal antibodies and tyrosine kinase inhibitors specifically targeting EGFR are the most well-studied and hold substantial promise of success. Several compounds of monoclonal antibodies and tyrosine kinase inhibitors… CONTINUE READING
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