Targeting effectors: the molecular recognition of Type III secreted proteins.


The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review. 
DOI: 10.1016/j.micinf.2010.02.003